range of eukaryotic and prokaryotic proteins involved in sensing Light,Oxygen or Voltage, hence the acronym LOV. Blue light irradiation of protein bound FMN causes a conformational change of phototropin that triggers auto phosphorylation and starts the sensory transduction cascade.There’re two different types of phototropins (PHOT 1 and PHOT 2) in Arabidopsis that exhibits overlapping function in addition to having unique physiological roles. In absence of light,FMNs are non covalently bonded to LOV domains.But in presence of blue light,they become covalently bonded to Cysteine residues in the polypeptides. Photoexcitaton of LOV results in activation of C- terminal kinase domain,leads to auto phosphorylation on multiple serine residues.
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When I was quite small, my family were Jehovah’s Witnesses. My big brothers remembered their Catholic beginnings, they remembered magical Christmases. My little brother and I did not, we’d never been Catholic yet. We used to get very sad that all of our friends had lovely Christmas or Hanukkah, and we did not. We’d pout. My big brothers tried their best to console us. Our best friends lived across the Awesome The collective Hound Mouth 500 racing houndmouth T shirt . Their dad was not home much, but he was a very stern man. He had quite the temper (when we grew up, we realized that he was always drunk, but when we were small he was just scary). He had a Doberman called Rex who we were all also terrified of. One year, I’m probably four or five, we’re sitting in my brothers’ room wistfully staring out the window at our friends playing with their new toys, wearing their Christmas sweaters, all that. The oldest two brothers, maybe trying to console us, convince us that we do not want Christmas at all. They tell us that Scary Dad is Santa Claus. They tell us that Rex the Doberman is actually Rudolph. Would we really want Rex landing on our roof? Would we really want Scary Dad judging whether we were naughty or nice, and sneaking into our house while we slept?
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